Pubblicazioni

Differential impact of MT1 and MT2 melatonin receptor deletion on biliary proliferation, senescence, and liver fibrosis during cholestatic liver injury

2017 - HEPATOLOGY

Wu, Nan; Kyritsi, Tina; Invernizzi, Pietro; Venter, Julie; Bernuzzi, Francesca; Meng, Fanyin; Sato, Keisaku; Gaudio, Eugenio; Francis, Heather L.; Zhou, Tianhao; Onori, Paolo; Franchitto, Antonio; Alpini, Gianfranco; Glaser, Shannon S.

Secretin receptor antagonist treatment reduces biliary damage and liver fibrosis in a mouse model of early stage primary biliary cholangitis (PBC), but not advanced PBC

2017 - HEPATOLOGYHEPATOLOGY

Kennedy, Lindsey; Francis, Heather L.; Venter, Julie; Hargrove, Laura; Wu, Nan; Invernizzi, Pietro; Eric Gershwin, M.; Bernuzzi, Francesca; Meng, Fanyin; Marzioni, Marco; Onori, Paolo; Franchitto, Antonio; Alvaro, Domenico; Gaudio, Eugenio; Glaser, Shannon S.; Alpini, Gianfranco

Gonadotropin-releasing hormone (GnRH) contributes to liver fibrosis in primary sclerosing cholangitis (PSC) through enhanced epithelial-mesenchymal transition (EMT) in small but increased senescence in large cholangiocytes

2016 - HEPATOLOGY

Kyritsi, T; Wu, N; Invernizzi, P; Venter, J; Zhou, Th; Sato, K; Bernuzzi, F; Mcdaniel, K; Onori, Paolo; Franchitto, Antonio; Gaudio, Eugenio; Francis, Hl; Glaser, Ss; Meng, F; Alpini, G.

Inhibition of the substance P/neurokinin-1 receptor (NK-1R) axis decreases liver fibrosis in the Mdr2(-/-) mouse model of primary sclerosing cholangitis (PSC) through changes in senescence in cholangiocytes and hepatic stellate cells

2016 - HEPATOLOGY

Wan, Y; Zhou, Th; Wu, N; Invernizzi, P; Standeford, Ha; Mcdaniel, K; Bernuzzi, F; Venter, J; Onori, Paolo; Gaudio, Eugenio; Franchitto, Antonio; Sato, K; Francis, Hl; Meng, Fy; Alpini, G; Glaser, Ss

Knockdown of the melatonin receptor, MT1, reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated (BDL) mice

2015 - HEPATOLOGYHEPATOLOGY

Wu, N; Meng, Fy; Wan, Y; Venter, J; Standeford, Ha; Francis, Hl; Kennedy, L; Han, Yy; Mcdaniel, K; Franchitto, Antonio; Onori, Paolo; Demorrow, S; Annable, T; Gaudio, Eugenio; Glaser, Ss; Alpini, G.

Down-regulation of the secretin/SR (SCT/SR) axis is coupled with functional biliary damage in dnTGF beta RII mice and human primary biliary cirrhosis (PBC)

2015 - HEPATOLOGYHEPATOLOGY

Kennedy, L; Glaser, Ss; Bernuzzi, F; Meng, Fy; Venter, J; Francis, Hl; Alvaro, D; Gershwin, Me; Franchitto, Antonio; Onori, Paolo; Demorrow, S; Marzioni, M; Gaudio, Eugenio; Invernizzi, P; Alpini, G.

The secretin receptor antagonist (SCT 5-27) reduces biliary hyperplasia and liver fibrosis in an animal model of primary sclerosing cholangitis

2015 - HEPATOLOGYHEPATOLOGY

Wu, N; Meng, Fy; Wan, Y; Venter, J; Bai, Hb; Avila, S; Mcdaniel, K; Standeford, Ha; Onori, Paolo; Gaudio, Eugenio; Alpini, G; Glaser, SS (Glaser

Knockout of the secretin/secretin receptor axis delays regeneration of small and large cholangiocytes by enhanced senescence following 70\% partial hepatectomy (PH)

2015 - HEPATOLOGYHEPATOLOGY

Wan, Y; Glaser, Ss; Wu, N; Meng, Fy; Venter, J; Mancinelli, Romina; Francis, Hl; Franchitto, Antonio; Onori, Paolo; Kyritsi, T; Avila, S; Carpino, G; Standeford, Ha; Alpini, G; Gaudio, Eugenio