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Relapses and treatment-related events contributed equally to poor prognosis in children with ABL-class fusion positive B-cell acute lymphoblastic leukemia treated according to AIEOP-BFM protocols

ABL-class fusions other than BCR-ABL1 characterize around 2-3% of precursor B-cell acute lymphoblastic leukemia. Case series indicated that patients suffering from these subtypes have a dismal outcome and may benefit from the introduction of tyrosine kinase inhibitors.

Allogeneic hematopoietic stem cell transplantation in leukocyte adhesion deficiency type I and III

Type I and III leukocyte adhesion deficiencies (LADs) are primary immunodeficiency disorders resulting in early death due to infections and additional bleeding tendency in LAD-III. The curative treatment of LAD-I and LAD-III is allogeneic hematopoietic stem cell transplantation (allo-HSCT). In this retrospective multicenter study, data were collected using the European Society for Blood and Marrow Transplantation registry; we analyzed data from 84 LAD patients from 33 centers, all receiving an allo-HSCT from 2007 to 2017.

Intra-European Mobility of Skilled Expatriates and Place-Identity: Interwoven Social Representations of Rome and Warsaw

This paper discusses the influence of social representations of a destination city on the motivation and development of individual mobility patterns, using questionnaires with a projective technique and guided interviews. The participants were 60 skilled expatriates in two different European capital cities: Italians residing in Warsaw and Poles residing in Rome. The study demonstrates the relevance of place-identity for the meaning of place within urban culture, in the context where global and local issues are interwoven.

Influence of systemic infection and comorbidities on rehabilitation outcomes in severe acquired brain injury

Severe infectious complications are a frequent problem in patients with disability due to a severe acquired brain injury. Previous studies reported that the rehabilitation outcome is significantly lower in patients colonized or infected. However, these results could be influenced by comorbidities of those patients admitted in rehabilitation hospital with a lower functional status.

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