Ricerc@Sapienza

Micronutrient deficiencies are relatively common, in particular iron and cobalamin deficiency, and may potentially lead to life-threatening clinical consequences when not promptly recognized and treated, especially in elderly patients. The stomach plays an important role in the homeostasis of some important hematopoietic micronutrients like iron and cobalamin, and probably in others equally important such as ascorbic acid, calcium, and magnesium.

OBJECTIVE Roux-en-Y gastric bypass (RYGB) characteristically enhances postprandial levels of glucagon-like peptide 1 (GLP-1), a mechanism that contributes to its profound glucose-lowering effects. This enhancement is thought to be triggered by bypass of food to the distal small intestine with higher densities of neuroendocrine L-cells.

Objective To assess the role of jejunum in insulin resistance in humans and in experimental animals.

Design Twenty-four subjects undergoing biliopancreatic diversion (BPD) or Roux-en-Y gastric bypass (RYGB) were enrolled. Insulin sensitivity was measured at baseline and at 1 week after surgery using oral glucose minimal model.

Obesity has become a global epidemic with a soaring economic encumbrance due
to its related morbidity and mortality. Amongst obesity-related conditions, cancer is
indeed the most redoubtable. Bariatric surgery has been proven to be the most
effective treatment for obesity and its associatedmetabolic and cardiovascular disorders.
However, the understanding of whether and how bariatric surgery determines a
reduction in cancer risk is limited. Obesity-related malignancies primarily include

Dear Authors, the Journal of Gastric Surgery (J Gastr Surg, JGS) is a peer-reviewed journal published and managed by the International Gastric Cancer Unit established between the Department of Surgical Sciences (Sapienza University), Department of Gastric Surgery (Fujian Medical University), Department of Digestive Surgery (St. Mary’s Hospital of Terni). J Gastr Surg publishes original articles, reviews, editorials and letters to the Editor. Gastric Surgeons all over the world are kindly invited to contribute to the growth of the Journal of Gastric Surgery.

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Emerging evidence suggests that bariatric surgery improves pregnancy outcomes of women with obesity by reducing the rates of gestational diabetes, pregnancy-induced hypertension, and macrosomia. However, it is associated with an increased risk of a small-for-gestational-age fetus and prematurity. Based on the work of a multidisciplinary task force, we propose clinical practice recommendations for pregnancy management following bariatric surgery.