The microinjection system enables the transfer of dissolved or suspended substances into single cells or into 3D cellular structures (organoids) under precise microscopic control using direct pressure. This system is paired with a micromanipulator that guides a fine glass capillary loaded with the injection sample, allowing it to puncture and penetrate the cell structure accurately.
The project proposed by the Department of Environmental Biology consists of an integrated “intelligent” Phytotron (Integrated Smart Phytotrone) which aims to carry out interdisciplinary experiments on the reactions of plants to different types of stress: pollution, pathogens, drought inter alia.
Lipids occur in fungi as major constituents of the membrane systems and minor component in the cell wall; they can store energy in the lipid bodies and, in some cases, they can act as intra-extracellular signals. Fungi contain a various set of lipids, including fatty acids, oxylipins, sphingolipids, phospholipids, glycolipids, and sterols. Current studies in lipids suggest their additional role in cell signalling; for instance, host-pathogen exchange lipid signals at the interface during their interaction.
Autophagy is a catabolic process strongly involved in the immune response, and its dysregulation contributes to the onset of several diseases including cancer. The human oncogenic gammaherpesviruses, EpsteinBarr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV), manipulate autophagy, either during the de novo infection or during the lytic reactivation, in naturally latently-infected lymphoma cells.
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