The Agilent 5977B GC/MSD is the latest in the series of most trusted single quadrupole GC/MS instruments. It is ideal for environmental, chemical, food, pharmaceutical, applications. It allows the analysis of a wide range of small metabolites including fatty acids, aminoacids, amines, organic acids, etc.
Caralluma fimbriata Wall. is currently used as a "natural slimming" food supplement, likely due to its content in pregnane glycosides. In the present study, a commercially available Caralluma fimbriata extract (Slimaluma®; CFE, 100 mg/kg) has been evaluated for its ability to affect the ingestive behaviour in female rats, also with reference to the modulation of the brain neuropeptides NPY and ORX.The interference of CFE with ?-amylase and lipase enzymes has been investigated in vitro, as possible peripheral mechanism of action.
The bystander effect (BE) is an important biological phenomenon that induces damages in distant and not directly affected by a chemical/physical stress cells. This effect, well known in ionizing radiation treatment, relies on reactive signals released by exposed cells and transmitted via cell–cell interaction or culture medium. In this study, cycloheximide (CHX)-induced apoptotic U937 cells and untreated THP-1 cells were chosen to investigate the chemical-induced BE.
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