Naringenin is a powerful inhibitor of SARS-CoV-2 infection in vitro
01 Pubblicazione su rivista
Clementi N., Scagnolari C., D'Amore A., Palombi F., Criscuolo E., Frasca F., Pierangeli A., Mancini N., Antonelli G., Clementi M., Carpaneto A., Filippini A.
ISSN: 1043-6618
Recently, an interesting review appeared in Pharmacological Research presented a list of candidate drugs against SARS-CoV-2 and COVID-19 [1]. In the present insight, we highlight novel experimental evidence that the flavanone Naringenin, targeting the endo-lysosomal Two-Pore Channels (TPCs), could be added to the list of potential weapons against SARS-CoV-2 infection and COVID-19 disease.