Risultati ricerca pubblicazioni

Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Saccoliti Francesco, Madia VALENTINA NOEMI, Tudino Valeria, DE LEO Alessandro, Pescatori Luca, Messore Antonella, DE VITA Daniela, Scipione Luigi, Brun Reto, Kaiser Marcel, Mäser Pascal, Magalhaes Calvet Claudia, K Jennings Gareth, M Podust Larissa, Costi Roberta, DI SANTO Roberto

Experimental study and computational modelling of cruzain cysteine protease inhibition by dipeptidyl nitriles

pubblicato su: PHYSICAL CHEMISTRY CHEMICAL PHYSICS - 2018

Dos Santos Alberto Monteiro, Cianni Lorenzo, De Vita Daniela, Rosini Fabiana, Leitão Andrei, Laughton Charles A, Lameira Jerônimo, Montanari Carlos A

Identification of Inhibitors to trypanosoma cruzi sirtuins based on compounds developed to human enzymes

pubblicato su: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2020

Matutino Bastos Tanira, Botelho Pereira Soares Milena, Haddad Franco Caio, Alcântara Laura, Antonini Lorenzo, Sabatino Manuela, Mautone Nicola, Holanda Freitas-Junior Lucio, Moraes Carolina Borsoi, Ragno Rino, Rotili Dante, Schenkman Sergio, Mai Antonello, Silvio Moretti Nilmar

Molecular design aided by random forests and synthesis of potent trypanocidal agents as cruzain inhibitors for Chagas disease treatment

pubblicato su: CHEMICAL BIOLOGY & DRUG DESIGN - 2020

de Albuquerque S., Cianni L., de Vita D., Duque C., Gomes A. S. M., Gomes P., Laughton C., Leitao A., Montanari C. A., Montanari R., Ribeiro J. F. R., da Silva J. S., Teixeira C.