Risultati ricerca pubblicazioni

Assessment of the cruzain cysteine protease reversible and Irreversible covalent inhibition mechanism

pubblicato su: JOURNAL OF CHEMICAL INFORMATION AND MODELING - 2020

Silva José Rogério A, Cianni Lorenzo, Araujo Deborah, Batista Pedro Henrique Jatai, de Vita Daniela, Rosini Fabiana, Leitão Andrei, Lameira Jerônimo, Montanari Carlos A

Synthesis and structure-activity relationship of nitrile-based cruzain inhibitors incorporating a trifluoroethylamine-based P2 amide replacement

pubblicato su: BIOORGANIC & MEDICINAL CHEMISTRY - 2019

Gomes Juliana C, Cianni Lorenzo, Ribeiro Jean, Dos Reis Rocho Fernanda, da Costa Martins Silva Samelyn, Batista Pedro Henrique Jatai, Moraes Carolina Borsoi, Franco Caio Haddad, Freitas-Junior Lucio H G, Kenny Peter W, Leitão Andrei, Burtoloso Antonio C B, de Vita Daniela, Montanari Carlos A

Molecular design aided by random forests and synthesis of potent trypanocidal agents as cruzain inhibitors for Chagas disease treatment

pubblicato su: CHEMICAL BIOLOGY & DRUG DESIGN - 2020

de Albuquerque S., Cianni L., de Vita D., Duque C., Gomes A. S. M., Gomes P., Laughton C., Leitao A., Montanari C. A., Montanari R., Ribeiro J. F. R., da Silva J. S., Teixeira C.