Risultati ricerca pubblicazioni

Synthesis and structure-activity relationship of nitrile-based cruzain inhibitors incorporating a trifluoroethylamine-based P2 amide replacement

pubblicato su: BIOORGANIC & MEDICINAL CHEMISTRY - 2019

Gomes Juliana C, Cianni Lorenzo, Ribeiro Jean, Dos Reis Rocho Fernanda, da Costa Martins Silva Samelyn, Batista Pedro Henrique Jatai, Moraes Carolina Borsoi, Franco Caio Haddad, Freitas-Junior Lucio H G, Kenny Peter W, Leitão Andrei, Burtoloso Antonio C B, de Vita Daniela, Montanari Carlos A

Leveraging the cruzain S3 subsite to increase affinity for reversible covalent inhibitors

pubblicato su: BIOORGANIC CHEMISTRY - 2018

Cianni Lorenzo, Sartori Geraldo, Rosini Fabiana, De Vita Daniela, Pires Gabriel, Lopes Bianca Rebelo, Leitão Andrei, Burtoloso Antonio C B, Montanari Carlos A

Naturally-occurring alkaloids of plant origin as potential antimicrobials against antibiotic-resistant infections

pubblicato su: MOLECULES - 2020

Casciaro B., Mangiardi L., Cappiello F., Romeo I., Loffredo M. R., Iazzetti A., Calcaterra A., Goggiamani A., Ghirga F., Mangoni M. L., Botta B., Quaglio D.

Oregonin from Alnus incana bark affects DNA methyltransferases expression and mitochondrial DNA copies in mouse embryonic fibroblasts

pubblicato su: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY - 2018

Krasilnikova Jelena, Lauberte Liga, Stoyanova Elena, Abadjieva Desislava, Chervenkov Mihail, Mori Mattia, De Paolis Elisa, Mladenova Vanya, Telysheva Galina, Botta Bruno, Kistanova Elena

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

pubblicato su: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY - 2019

Rotondi G., Guglielmi P., Carradori S., Secci D., De Monte C., De Filippis B., Maccallini C., Amoroso R., Cirilli R., Akdemir A., Angeli A., Supuran C. T.

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Talapatra Sandeep K., Tham Chuin Lean, Guglielmi Paolo, Cirilli Roberto, Chandrasekaran Balakumar, Karpoormath Rajshekhar, Carradori Simone, Kozielski Frank

Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis

pubblicato su: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY - 2019

Di Paolo V., Fulci C., Rotili D., Sciarretta F., Lucidi A., Morozzo della Rocca B., De Luca A., Rosato A., Quintieri L., Caccuri A. M.

MAO inhibitors and their wider applications: a patent review

pubblicato su: EXPERT OPINION ON THERAPEUTIC PATENTS - 2018

Carradori Simone, Secci Daniela, Petzer Jacques P.

Natural modulators of nonalcoholic fatty liver disease: mode of action analysis and in silico ADME-Tox prediction

pubblicato su: TOXICOLOGY AND APPLIED PHARMACOLOGY - 2017

Al Sharif Merilin, Alov Petko, Vitcheva Vessela, Diukendjieva Antonia, Mori Mattia, Botta Bruno, Tsakovska Ivanka, Pajeva Ilza

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

Loubidi Mohammed, Jouha Jabrane, Tber Zahira, Khouili Mostafa, Suzenet Franck, Akssira Mohamed, Erdogan Mümin Alper, Köse Fadime Aydın, Dagcı Taner, Armagan Güliz, Saso Luciano, Guillaumet Gérald

9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a potentially novel antiplatelet drug which antagonizes the effect of thromboxane A2

pubblicato su: MEDICINAL CHEMISTRY - 2018

Applová Lenka, Veljović Elma, Muratović Samija, Karlíčková Jana, Macáková Kateřina, Završnik Davorka, Saso Luciano, Durić Kemal, Mladĕnka Přemysl

Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 integrase and reverse transcriptase associated ribonuclease H inhibitors

pubblicato su: ANTIVIRAL RESEARCH - 2020

Esposito F., Sechi M., Pala N., Sanna A., Koneru P. C., Kvaratskhelia M., Naesens L., Corona A., Grandi N., di Santo R., D'Amore V. M., Di Leva F. S., Novellino E., Cosconati S., Tramontano E.