Title |
Published on |
Year |
KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression |
BRITISH JOURNAL OF CANCER |
2020 |
KSHV dysregulates bulk macroautophagy, mitophagy and UPR to promote endothelial to mesenchymal transition and CCL2 release, key events in viral-driven sarcomagenesis |
INTERNATIONAL JOURNAL OF CANCER |
2020 |
BFRF1 protein is involved in EBV-mediated autophagy manipulation |
MICROBES AND INFECTION |
2020 |
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway |
FRONTIERS IN ONCOLOGY |
2020 |
Viral Infection and Autophagy Dysregulation: The Case of HHV-6, EBV and KSHV |
CELLS |
2020 |
EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation |
AUTOPHAGY |
2019 |
Stat3 phosphorylation affects p53/p21 axis and KSHV lytic cycle activation |
VIROLOGY |
2019 |
Kaposi Sarcoma Herpes Virus (KSHV) infection inhibits macrophage formation and survival by counteracting Macrophage Colony-Stimulating Factor (M-CSF)-induced increase of Reactive Oxygen Species (ROS), c-Jun N-terminal kinase (JNK) phosphorylation and autophagy |
THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY |
2019 |
Quercetin interrupts the positive feedback loop between STAT3 and IL-6, promotes autophagy, and reduces ROS, preventing EBV-driven B cell immortalization |
BIOMOLECULES |
2019 |
EBV up-regulates PD-L1 on the surface of primary monocytes by increasing ROS and activating TLR signaling and STAT3 |
JOURNAL OF LEUKOCYTE BIOLOGY |
2018 |
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways |
JOURNAL OF NUTRITIONAL BIOCHEMISTRY |
2017 |
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy |
SCIENTIFIC REPORTS |
2017 |
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation |
CELLULAR SIGNALLING |
2017 |
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells |
FREE RADICAL BIOLOGY & MEDICINE |
2017 |
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death |
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH |
2017 |
KSHV reduces autophagy in THP-1 cells and in differentiating monocytes by decreasing CAST/calpastatin and ATG5 expression |
AUTOPHAGY |
2016 |
Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma |
THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY |
2016 |
Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future |
BIOMED RESEARCH INTERNATIONAL |
2015 |
PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction |
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH |
2015 |
Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses |
JOURNAL OF IMMUNOLOGY RESEARCH |
2015 |