Roberta Chiaraluce | Ricerc@Sapienza

Roberta Chiaraluce

Professore Associato

Struttura:

DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"

E-mail:

roberta.chiaraluce@uniroma1.it

Pagina istituzionale corsi di laurea

Curriculum Sapienza

Publications

Title	Published on	Year
Effect of bet missense mutations on bromodomain function, inhibitor binding and stability	PLOS ONE	2016
Chaperones, chaperonins and heat-shock proteins	eLS	2015

ERC

LS1_2
LS1_4
LS1_11

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Keywords

protein stability

missense variants

Progetti di Ricerca

Erk1 and cancer. Are this protein and its natural variants a special hotspot for mutations?
The human frataxin variants found in carcinoma cells display different functional activity and conformational stability compared to the wild type enzyme.

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