KEY WORDS: Diabetes - Cardiovascular comorbidity - Acute cholecystitis - Laparoscopy - Conversion rate - Timing

Impact of cardiovascular/diabetic comorbidity on conversion rate during laparoscopic cholecystectomy for acute cholecystitis. A multi-center study on early versus very delayed approach

Background. The impact of diabetes and cardiovascular comor- bidity on laparoscopic cholecystectomy has been long debated, evalua- ting them as risk factors for conversion to an open procedure especially in patients with acute cholecystitis: an “early” procedure, as suggested by 2013 Tokyo guidelines, has been compared to a “very delayed” one in patients under anticoagulant/antiplatelet therapy or treated for dia- betes and referred by medical wards to surgery after the acute period.

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