Rejuvenating pheidippides and the evergreen benefits of endurance training
We welcome the paper by Bhuva et al. (1) who investigated whether real-world exercise training for a first-time marathon can reverse age-related aortic stiffening, concluding that training even at relatively low exercise intensity reduces central blood pressure and aortic stiffness, equivalent to a 4-year reduction in vascular age. Nonetheless, although we found these data particularly interesting and novel, the report raises additional issues that should be addressed by the authors. First, only marathon finishers were included in the study.