A rare case of omental extra-gastrointestinal stromal tumor showing two coexisting mutations on exon 14 of the PDGFRA gene
Gastrointestinal stromal tumors (GISTs) are neoplasms arising
from mesenchymal cells localized into the muscularis propria
of the gastrointestinal (GI) tract [1]; 5% of GISTs are extra-GISTs
(EGISTs), as they differently originate from adipose tissue adjacent
to the GI tract (omentum and mesentery) or from the pancreas
[2]. So far, both GISTs and EGISTs have been managed
indistinctively by combining surgery, histopathological distinctive
features, imaging, and molecular analysis. Moreover, despite