photobiomodulation | Ricerc@Sapienza

Management of medication-related osteonecrosis of the jaw (MRONJ) using leukocyte- and platelet-rich fibrin (L-PRF) and photobiomodulation: a retrospective study

Background. The aim of this study was to compare retrospectively the effect of three
different treatment protocols on the healing outcome in patients with established medication-related
osteonecrosis of the jaw (MRONJ). Methods. A total of 34 MRONJ patients were recruited from the
Department database and were divided according to the treatment protocols in a study group (G1)
and two control groups (G2 and G3). G1 was treated with antibiotic therapy, surgery, leukocyte- and

Polarized polychromatic noncoherent light (bioptron light) as adjunctive treatment in chronic oral mucosal pain: a pilot study

Objective: Aim of this study was to assess the efficacy of polarized polychromatic noncoherent light (Bioptron light) in the treatment of chronic oral mucosal pain (COMP). Patients and methods: Twenty-two patients affected by COMP were treated with standardized pharmacological protocols in association with Bioptron light (90 W; light wavelength = 480-3400 nm; degree of polarization = 95%; specific power density = 40 mW/cm 2 ; energy density = 2.4 J/cm).