Effects of ibuprofen administration timing on oral surgery pain: a randomized clinical trial
Objective This study aimed to compare the analgesic effect of ibuprofen 400 mg given 30 minutes before or immediately after third molars surgery under local anaesthesia. Materials and Methods The single‐center, randomized, split‐mouth, triple‐blind, clinical trial involved 38 outpatients, for a total of 76 bilateral symmetrical fully bone impacted mandibular third molars. Each patient was undergone to separate surgical sessions for the right and left side, and ibuprofen was randomly administered 30 minutes before or immediately after the intervention.