Healing of intrabony defects following regenerative surgery by means of single-flap approach in conjunction with either hyaluronic acid or an enamel matrix derivative: a 24-month randomized controlled clinical trial
Objectives The aim of this randomized controlled clinical trial was to compare the clinical outcomes obtained in intrabony
defects following regenerative periodontal surgery using the single-flap approach (SFA) in conjunction with either hyaluronic
acid (HA) or enamel matrix derivative (EMD).
Materials and methods Thirty-two intrabony defects in 32 healthy subjects were randomly assigned: HA (test group) or EMD
(control group). Clinical attachment level (CAL), probing depth (PD), gingival recession (REC), and bleeding on probing (BOP)