The quest toward a specific biomarker for migraine stands among the biggest challenges of the last 50 years. Electrophysiological techniques are particularly suitable to study the nervous system in human beings. They are noninvasive, riskless and quite easy to perform and have a temporal resolution that cannot be achieved with other methods.
Migraine is a complex polygenic disorder of the brain. Specific genes might be responsible for the condition due to the considerable clinical, epidemiological and evolutionary variability and interictal neurophysiological properties. Several studies have found that abnormal processing of a wide range of sensory stimuli is characteristic between attacks of patients that suffer from migraines. These neurophysiological abnormalities were significantly correlated between children that have migraines and their affected parents.
© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma
