Peptides with regularly alternating enantiomeric sequence: from ion channel models to bioinspired nanotechnological applications
Peptides are versatile building blocks that have been extensively used as peptide-based organizers to generate bioinspired hybrid materials. Among them, those peptides characterized by regularly alternating enantiomeric sequences (L,D-peptides) have attracted much interest. Their structures, which are not accessible to the corresponding homochiral peptides, have been exploited to achieve hybrid conjugates, the chemical and structural properties of which can be predetermined by correct design.