thalassemia | Ricerc@Sapienza

COVID-19 pneumonia and pulmonary microembolism in a patient with B-thalassemia major

We think that thalassemia is not necessarily a cause of aggravation of the clinical
course in COVID-19; however, certain key factors must be considered, such as the
anemic condition, the likely pathogenic role of the virus on hemoglobin, and the
hypercoagulable state to prevent any complications.

Advances in thermoanalytical techniques: may aspirin interfere with ß-thalassemia diagnosis?

Thermogravimetry coupled with chemometrics has proved to be a rapid and cost-effective diagnostic tool for β-thalassemia screening. This model, consisting of Partial Least Square-Discriminant Analysis (PLS-DA), permitted the discrimination of thalassemic patients and healthy individuals, using thermogravimetric curves of blood samples. In this study, the impact of aspirin on the capability of the TGA/chemometric validated model to screen for thalassemia was investigated.