HPLC–MS-MS

Accelerated Extraction and Analysis of Ethyl Glucuronide in Hair by Means of Pressurized Liquid Extraction Followed by Liquid Chromatography-Tandem Mass Spectrometry Determination

The measurement of ethyl glucuronide (EtG) in hair is an established practice to evaluate alcohol consumption habits of the donors, nevertheless analytical variability has shown to be an important factor to be considered: measured EtG values can vary significantly as a consequence of analyte wash-out during decontamination, pulverization of samples, extraction solvent and incubation temperature.

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