inborn errors of immunity

Immunodeficiency Centre

Immunodeficiency Centre

The Immunodeficency Centre is dedicated to understanding the genetic, molecular, and immunological mechanisms underlying the Inborn Errors of Immunity (IEIs), a heterogeneous group of rare disorders characterized by defects in immune system development, regulation, and function. These conditions predispose patients to recurrent and severe infections, immune dysregulation, autoimmunity, autoinflammation, allergy, and malignancies.

Consensus of the Italian Primary Immunodeficiency Network on transition management from pediatric to adult care in patients affected with childhood-onset inborn errors of immunity

Medical advances have dramatically improved the long-term prognosis of children and adolescents with inborn errors of immunity (IEIs). Transfer of the medical care of individuals with pediatric IEIs to adult facilities is also a complex task because of the large number of distinct disorders, which requires involvement of patients and both pediatric and adult care providers. To date, there is no consensus on the optimal pathway of the transitional care process and no specific data are available in the literature regarding patients with IEIs.

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