Extracorporeal CO2 removal may improve renal function of patients with acute respiratory distress syndrome and acute kidney injury. an open-label, interventional clinical trial
Attenuation of inflammatory and apoptotic responses in patients with acute respiratory distress syndrome (ARDS) has been associated with a reduction in end-organ failure and the improvement in outcome observed with conventional protective ventilation (1). Recent data show that further reductions of Vt improve outcomes, but extracorporeal CO2 removal (ECCO2R) is needed to manage respiratory acidosis (2).