Age related changes seen in human cornea in formalin fixed sections and on biomicroscopy in living subjects: a comparison
The purpose of our experimental research was to assess the effects of aging on the main corneal structures in healthy corneas. Small, human cornea samples were collected from 20 Caucasian subjects during surgery for traumatic lesions to the eye. Ten subjects were adults (mean age 28 years) and ten were elderly (mean age 76 years). Morphological analysis was carried out using light microscopy and electron microscopy. Another 40 patients (20 young: mean age ˂ 30 yrs; 20 elderly: mean age ˃ 70yrs) were studied in vivo by confocal microscopy.