Ricerc@Sapienza

Background: In order to explore the possible association between chronotype and risk of medication errors and chronotype in Italian midwives, we conducted a web-based survey. The questionnaire comprised three main components: (1) demographic information, previous working experience, actual working schedule; (2) individual chronotype, either calculated by Morningness–Eveningness Questionnaire (MEQ); (3) self-perception of risk of medication error.

We aimed to evaluate quality of sleep and self-perception risk of medication errors, in a significantly-sized sample of nurses in Italy, using a web survey.

Cannabinoid drugs often induce biphasic effects on cognitive and emotional behavior depending on the level of stress and emotional arousal at the time of drug consumption. The effects of stress on endocannabinoids appear to be regionally specific and time-dependent relative to exposure to stress. Stress-induced changes in corticosterone affect memory.

Stress-induced changes in corticosterone affect memory. The endocannabinoid system appears as an emotional buffer in stress regulation. We evaluated how different stress intensities after encoding influence rat short-term memory in an object recognition task, whether the effects depend on circadian variation of corticosterone and if exogenous augmentation of anandamide levels could restore any observed impairment.

Cannabinoid drugs often induce biphasic effects on cognitive and emotional behavior depending on the level of stress and emotional arousal at the time of drug consumption. The effects of stress on endocannabinoids appear to be regionally specific and time-dependent relative to exposure to stress. Stress-induced changes in corticosterone affect memory.

The endocannabinoid system plays a key role in the control of emotional responses to environmental challenges. CB1 receptors are highly expressed within cortico-limbic brain areas, where they modulate stress effects on memory processes. Glucocorticoid and endocannabinoid release is influenced by circadian rhythm.

Knowledge of animals’ hormonal status is important for conservation studies in wild or semi-free-ranging conditions as well as for behavioural and clinical experiments conducted in laboratory research, mostly performed on rats and mice. Faecal sampling is a useful non-invasive method to obtain steroid hormone assessments. Nevertheless, in laboratory studies, unlike other contexts, faecal sampling is less utilised. One of the issues raised is the necessity to collect samples belonging to different animals, separately.