Endogenous and exogenous ligands

New trends in the pharmacological intervention of PPARs in obesity: Role of natural and synthetic compounds_

Obesity is a major health concern for a growing fraction of the population, with the prevalence of obesity and its related metabolic disorders not being fully understood. Over the last decade, many attempts have been undertaken to understand the mechanisms at the basis of this condition, in which the accumulation of fat occurring in adipose tissue, leads to the pathogenesis of obesity related disorders.

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