Ricerc@Sapienza

Background: Preliminary evaluations of behavioral interventions, referred to as pilot studies, predate the conduct of many large-scale efficacy/effectiveness trial. The ability of a pilot study to inform an efficacy/effectiveness trial relies on careful considerations in the design, delivery, and interpretation of the pilot results to avoid exaggerated early discoveries that may lead to subsequent failed efficacy/effectiveness trials. “Risk of generalizability biases (RGB)” in pilot studies may reduce the probability of replicating results in a larger efficacy/effectiveness trial.

Scalability and robustness are not an issue when compression is applied for massive data storage, in the context of distributed computing. Speeding up on-the-fly compression for data transmission is more controversial. In such case, a compression
technique merging together an adaptive and a non-adaptive approach has to be considered. A practical implementation of LZW (Lempel, Ziv and Welch) compression,called LZC (C indicates the Unix command ’compress’), has this characteristic. The