Ricerc@Sapienza

Background: Sjögren’s Syndrome (SS) is the second most common autoimmune rheumatic disease after rheumatoid arthritis and affects approximately 1 to 3% of the population. Most patients affected by Sjögren’s syndrome manifest otorhinolaryngological involvement, such as glandular, ocular, oral, otological, pharyngeal, laryngeal and sinonasal symptoms. Objective: The aim of this article is to emphasize the otorhinolaryngological manifestations of SS.

Background: patients with laryngopharyngeal reflux (LPR) showed detectable levels of tear pepsin that explain the nasolacrimal obstruction. The purpose of this study was to determine whether patients with LPR show ocular surface changes and to investigate the relationship between lacrimal pepsin concentration and ocular alterations. Methods: Fifty patients with positive endoscopic signs for LPR and an equal or higher score of 13 and 7 for Reflux Symptom Index and Reflux Finding Score were enrolled.