Ricerc@Sapienza

An optimal control design approach is applied to a novel HIV/AIDS model to reduce the infection diffusion. Two classes of susceptible subjects, the wise one and the incautious ones, and three classes of infectious subjects, the ones not aware of their condition and the subjects in the pre-aids or in the aids status, are considered. The control input, represented by information campaigns and the medication action, is designed by means of a linear quadratic approach on the linearized model.

The aim of this paper is to propose an optimal control strategy to face the propagation effects of a virus
outbreak on a network; a recently proposed model is integrated and analysed. Depending on the specific
model caracteristics, the epidemic spread could be more or less dangerous leading to a virus free or to a virus
equilibrium. Two possible controls are introduced: a test on the computers connected in a network and the
antivirus. In a condition of limited resources the best allocation strategy should allow to reduce the spread of

In this paper the problem of modeling and controlling the measles epidemic spread is faced. A new model
is proposed and analysed; besides the categories usually considered in measles modeling, the susceptible,
the exposed, the infected, the removed and, less frequently, the quarantine individuals, two new categories
are herein introduced: the immunosuppressed subjects, that can not be vaccinated, and the patients with an
additional complication, not risky by itself but dangerous if caught togeter with the measles. These two