Prediction of osteophytes relevance in human osteoarthritic femur head from load pattern rearrangement simulations: an integrated fem study.
Introduction: Osteoarthritis (OA) is the most common degenerative joint disease and it is mainly characterized by articular cartilage damage, synovial fibrosis and osteophyte formation. Osteophytes are osteo-cartilaginous outgrowths that involve the bone structure of osteoarthritic joints. In this study we analyzed how osteophytes evolution leads to a rearrangement of the stresses and strains within the subchondral trabecular bone.