ATTRv amyloidosis Italian Registry: clinical and epidemiological data
Introduction: ATTRv amyloidosis is worldwide spread with endemic foci in Portugal and Sweden, Japan, Brazil, Maiorca, and Cyprus. A national Registry was developed to characterise the epidemiology and genotype-phenotype correlation of ATTRv amyloidosis in Italy and to allow a better planning of diagnostic and therapeutic services. Methods: Fifteen Italian referral centres for amyloidosis spread all over the country have contributed to the Registry. Results: Four-hundred-forty-seven subjects were enrolled, 187 asymptomatic carriers and 260 affected patients.