Subclinical epileptiform activity during sleep in Alzheimer's disease and mild cognitive impairment
OBJECTIVE:
Recent findings suggested that subclinical epileptiform activity is prevalent during sleep in a significant proportion of Alzheimer's Disease (AD) patients.
THE AIMS OF OUR STUDY WERE:
(A) comparing the frequency of subclinical epileptiform activity during the sleep in a sample diagnosed with 'probable' AD and Mild Cognitive Impairment (MCI) due to AD, and in healthy subjects; (B) evaluating epileptiform EEG activity as a function of different sleep stages within a well-controlled polysomnographic setting.
METHODS: