5) tetrakisphosphate

Editorial: Membrane lipids in T cell functions

Plasma membrane lipids play essential roles in regulating T cell signaling, differentiation, and
effector functions. The major lipid species in the plasma membrane are glycerophospholipids,
sphingolipids, and sterol lipids. TCR and costimulatory molecules lead to profound changes in
the composition, distribution, and dynamic of plasma membrane lipids. For instance, cholesterol,
sphingomyelin, and saturated phosphocholine are enriched at the contact zone between T cells

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