Ricerc@Sapienza

Corneal cross-linking (CXL) consists in the induction of a tissue biomechanical alteration, which leads to a stiffening, and strengthening of the ectatic corneal tissue. The treatment involves the use of the riboflavin (Vitamin B2) as a photoinducer, an ultraviolet light source and a photochemical reaction that creates a chemical bond between collagen fibrils. The safety of the ultraviolet light parameters depends on wavelength, irradiance and time of irradiation.