Addiction Alcohol use disorders Antioxidant polyphenols Resveratrol BDNF

Oxidative stress inhibition by resveratrol in alcohol dependent mice

Objective

uncontrolled ingestion of alcohol has dramatic consequences on the entire organism also associated with the oxidation process induced by alcohol by elevating radical oxygen species (ROS). Resveratrol, a non-flavonoid phenol, shows well-documented antioxidant properties. We investigated the potential antioxidant ability of this natural compound in a mouse model of alcohol addiction.
Methods

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