adrenal disorders

Adrenal and pituitary disorders

Adrenal and pituitary disorders

All glands are created equal, but some glands are more equal than the others. Understanding the complications and the development of new treatments for pituitary and adrenal disorders has exploded in the past decades. We have contributed to investigating and systematically analyzing the available evidence. Our favorite condition is the most difficult of them all, Cushing's syndrome. Nonetheless, the international community has also appreciated our research on obesity, the metabolic effect of GH, and the treatments used to manage its excess.

Abnormal linear growth in paediatric adrenal diseases: Pathogenesis, prevalence and management

Abnormal adrenal function can interfere with linear growth, potentially causing either acceleration or impairment of growth in paediatric patients. These abnormalities can be caused by direct effects of adrenal hormones, particularly glucocorticoids and sex steroids, or be mediated by indirect mechanisms such as the disturbance of the growth hormone-insulin-like growth factor-1 axis and aromatization of androgens to oestrogens. The early diagnosis and optimal treatment of adrenal disorders can prevent or minimize growth disturbance and facilitate improved height gain.

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma