Ricerc@Sapienza

Adrenal cavernous hemangioma is an extremely rare benign tumor. To date, less than 70 cases have been reported in the literature. In most of the cases, the tumor is hormonally silent, discovered incidentally and the diagnosis is made postoperatively. Pre-operative differentiation between this benign tumor and other malignant adrenal tumors is challenging. In this article we present a case of a non-functioning adrenal incidentaloma that was managed by laparoscopic adrenalectomy. The post-operative histological diagnosis was adrenal cavernous hemangioma.

Pheochromocytoma (PHEO), a rare catecholamine-producing tumor, is a disease entity with variable clinical
manifestations. The classic triad of symptoms are palpitations, headaches, and diaphoresis, but the signs and
symptoms are wide ranging and mainly reflect the hemodynamic and metabolic actions of the catecholamines
produced and secreted by the tumor. We describe the rare case of a patient affected by nonfunctioning and
asymptomatic PHEO associated with the incidental discovery of renal oncocytoma, and review the literature.

ABSTRACT
Introduction: Pheochromocytoma (PHEO) is a rare catecholamine-producing tumour arising from chromaffin cells in the sympatho-adrenal
system, and can present as asymptomatic adrenal incidentaloma (AI).
Patient: We describe the case of a 61-year-old woman with a right adrenal mass incidentally discovered, who was biochemically characterized
with subclinical hypercortisolism (SH). The patient was scheduled for adrenalectomy because of increasing seizure of the right adrenal