Anorectal function and quality of life after chemoradiotherapy in patients with canal carcinoma
Background A retrospective study was conducted to evaluate sphincter function and quality of life (QoL) in
patients treated with radiotherapy and concurrent chemotherapy (CRT) for anal canal cancer.
Materials and Methods From 1998 to 2010, patients with anal canal cancer treated with CRT were eligible.
Radiation dose was 59.4 Gy (1.8 Gy/ fraction) and the chemotherapy regimen was 5-fluorouracil and mitomycin
C. Anorectal function was investigated by anorectal manometry and transrectal ultrasound. QoL was assessed