A versatile aptasensor material for lab-on-chip analytical applications
Here, we present a LoC device functionalized with an aptasensor material based on poly 2-(hydroxyethylmethacylate) (PHEMA) brushes, for monitoring the presence of the mycotoxin Ochratoxin A (OTA). OTA has been recognized toxic for different organs and its early detection in food commodities, by using this LoC in the production site, would reduce the risks for human and animal health. The aptamer, having high affinity versus OTA (OTA-aptamer), is immobilized into the PHEMA layer grown within a microfluidic channel.