Correlative microscopy is an approach which benefits from imaging of the same object by different techniques. Correlation between the data, measured by two or more independent methods, can provide a piece of further information about the sample, which could be too complicated to analyze by those methods separately.
The aim of this in vitro study is to prepare and characterize drug free and pentamidine loaded chitosan glutamate coated niosomes for intranasal drug delivery to reach the brain through intranasal delivery. Mucoadhesive properties and stability testing in various environments were evaluated to examine the potential of these formulations to be effective drug delivery vehicles for intranasal delivery to the brain. Samples were prepared using thin film hydration method.
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