Ricerc@Sapienza

Previous studies have shown inconsistent results regarding the effect of the Val158Met polymorphism of the catechol-O-methyltransferase (COMT) gene on personality and cognition. Here, nonclinical Caucasian university students of Italian origin were administered the Temperament and Character Inventory-Revised, Tellegen Absorption Scale, Differential Attentional Processes Inventory, and Waterloo-Stanford Group Scale of Hypnotic Susceptibility.

Over the last five decades, a number of biological oriented personality theories have been proposed
to explain how anatomical and functional differences in the human brain are responsible for
individual differences in personality. Catechol-O-methyltransferase (COMT) gene for the Val158Met
single nucleotide polymorphism (rs4680) is known to influence the activity of the enzyme responsible
for dopamine metabolism and has been linked with various aspect of personality dimensions and