A new role for Drosophila Aurora-A in maintaining chromosome integrity
Aurora-A is a conserved mitotic kinase overexpressed in many types of cancer. Growing evidence shows that Aurora-A plays a
crucial role in DNA damage response (DDR) although this aspect has been less characterized. We isolated a new aur-A mutation, named aur-A949, inDrosophila, and we showed that it causes chromosome aberrations (CABs). In addition, aur-A