axillary dissection | Ricerc@Sapienza

Retrospective evaluation of the effectiveness of a synthetic glue and a fibrin-based sealant for the prevention of seroma following axillary dissection in breast cancer patients

Introduction: Seroma formation represents one of the most frequent postoperative
complications of axillary dissection in breast cancer (BC) patients. We aimed to
retrospectively explore the effectiveness of the intraoperative use of a synthetic
cyanoacrylate glue (specifically Glubran®2) vs. the intraoperative use of a fibrin sealant
(specifically Tisseel) in reducing seroma formation compared to the use of nonsealant in
BC patients who underwent breast surgery and axillary dissection.

Trends in axillary lymph node dissection for early-stage breast cancer in Europe: Impact of evidence on practice

Background: Data from recently published trials have provided practice-changing recommendations for the surgical approach to the axilla in breast cancer. Patients with T1-2 lesions, treated with breast conservation, who have not received neoadjuvant chemotherapy and have 1–2 positive sentinel nodes (Z0011-criteria) may avoid axillary lymph node dissection (ALND). We aim to describe the dissemination of this practice in Europe over an extended period of time.