bladder cancer staging

Integrated Diagnostic in Bladder Cancer

Integrated Diagnostic in Bladder Cancer

The research activities in the field of integrated diagnostics for bladder cancer focus on advancing multiparametric MRI (mpMRI) as a quantitative and standardized tool for precision oncology. Core developments include the optimization of loco-regional staging and the creation and validation of the VI-RADS score, designed to differentiate muscle-invasive (MIBC) from non–muscle-invasive bladder cancer (NMIBC). This framework, is done under the umbrella of the American College of Radiology VI-RADS committee, of which Prof. Panebianco is Chair.

Preoperative detection of Vesical Imaging-Reporting and Data System (VI-RADS) score 5 reliably identifies extravesical extension of urothelial carcinoma of the urinary bladder and predicts significant delayed time to cystectomy: time to reconsider th

Objectives: (I) To determine Vesical Imaging-Reporting and Data System (VI-RADS) score 5 accuracy in predicting locally advanced bladder cancer (BCa), so as to potentially identify those patients who could avoid the morbidity of deep transurethral resection of bladder tumour (TURBT) in favour of histological sampling-TUR prior to radical cystectomy (RC). (II) To explore the predictive value of VI-RADS score 5 on time-to-cystectomy (TTC) outcomes.

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