cell metabolism

Stazione di lavoro ipossica

Lingua Italiano

Stazione di lavoro ipossica con Seahorse XFe i2 Cables per Seahorse models XFe 96 e XFe 24.

SEAHORSE XF 96

Lingua Italiano

ANALIZZATORE DI FLUSSI ENERGETICI CELLULARI

RNA-mediated modulation of cell metabolism

The perception of RNA–protein interactions is currently changing from a protein-centric approach, in which proteins regulate the expression and activity of RNA, to a more complex view, in which RNA molecules can directly regulate protein's function and thus cell behavior, in a process called riboregulation.

Informazioni

Struttura
Spin OFF
KET
Keywords
Progetti principali
Altre informazioni

Componenti del gruppo

Nome	E-mail

Collaboratori nazionali ed internazionali

Laboratori

Pubblicazioni

Brevetti

Progetti di ricerca

ERC

ERC	Descrizione

Infrastrutture

Leggi tutto su RNA-mediated modulation of cell metabolism

Shmt2: a stat3 signaling new player in prostate cancer energy metabolism

Prostate cancer (PCa) is a multifactorial disease characterized by the aberrant activity of different regulatory pathways. STAT3 protein mediates some of these pathways and its activation is implicated in the modulation of several metabolic enzymes. A bioinformatic analysis indicated a STAT3 binding site in the upstream region of SHMT2 gene. We demonstrated that in LNCaP, PCa cells' SHMT2 expression is upregulated by the JAK2/STAT3 canonical pathway upon IL-6 stimulation.