Ricerc@Sapienza

Our research investigates the mechanisms underlying cellular recovery, with a particular emphasis on the role of nutrients as active modulators of repair and adaptation processes, especially in neural models exposed to oxidative stress or harboring rare metabolic mutations. We study how micronutrients—at both physiological and pharmacological doses—affect neural-like cells, focusing on metabolism as a potential upstream modulator rather than a downstream consequence.

The perception of RNA–protein interactions is currently changing from a protein-centric approach, in which proteins regulate the expression and activity of RNA, to a more complex view, in which RNA molecules can directly regulate protein's function and thus cell behavior, in a process called riboregulation.