Chemoradiotherapy

Sharp Lp estimates for Schrödinger groups on spaces of homogeneous type

We prove an Lp estimate (Equation Presented) for the Schrödinger group generated by a semibounded, self-adjoint operator L on a metric measure space X of homogeneous type (where n is the doubling dimension of X). The assumptions on L are a mild Lp0 → Lp' 0 smoothing estimate and a mild L2 → L2 off-diagonal estimate for the corresponding heat kernel e -tL. The estimate is uniform for φ varying in bounded sets of S(R), or more generally of a suitable weighted Sobolev space.

Comparison of Different Nodal Staging in Patients with Locally Advanced Mid-low Rectal Cancer after Long-term Neoadjuvant Chemoradiation Therapy

Background/Aim: The aim of this study was to compare the ability of different lymph nodal staging systems to predict cancer recurrence in a multicenter European series of patients who underwent proctectomy after neoadjuvant chemoradiotherapy for locally advanced rectal cancer. Patients and Methods: Data on 170 consecutive patients undergoing proctectomy after neoadjuvant therapy for cT3-4 or cN+ rectal adenocarcinoma were retrieved from the European MRI and Rectal Cancer Surgery database.

Diffusion-weighted magnetic resonance imaging in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy

Abstract
Purpose: To analyze diffusion-weighted magnetic resonance imaging (DW-MRI) for treatment response assessment in locally advanced
rectal cancer (LARC).
Patients and methods: Patients with histologically proven rectal adenocarcinoma, stage IIeIII disease, were enrolled and underwent surgery
following neoadjuvant chemoradiotherapy (nCRT). All patients were referred for a DW-MRI protocol on a 3 Tesla MR-system, consisting

MR-based artificial intelligence model to assess response to therapy in locally advanced rectal cancer

Purpose: To develop and validate an Artificial Intelligence (AI) model based on texture analysis of high-resolution T2 weighted MR images able 1) to predict pathologic Complete Response (CR) and 2) to identify non-responders (NR) among patients with locally-advanced rectal cancer (LARC) after receiving neoadjuvant chemoradiotherapy (CRT). Method: Fifty-five consecutive patients with LARC were retrospectively enrolled in this study. Patients underwent 3 T Magnetic Resonance Imaging (MRI) acquiring T2-weighted images before, during and after CRT.

Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery in locally advanced rectal cancer: preliminary results of a phase II study

PURPOSE: To report preliminary results of induction chemotherapy (IC) followed by neoadjuvant chemoradiotherapy (CRT) and surgery in locally advanced rectal cancer (LARC) patients.MATERIALS AND METHODS: This is the preliminary evaluation of a phase II study. Patients with histologically proven rectal adenocarcinoma, stage II-III disease, who met the inclusion criteria, received induction FOLFOXIRI (5-FU, leucovorin, oxaliplatin and irinotecan) regimen in combination with targeted agents followed by CRT and surgery.

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