Ricerc@Sapienza

BACKGROUND:
Early onset (?50y) colorectal carcinomas (EO-CRCs) are increasing in incidence according to epidemiological data. We investigated clinical-pathological, molecular features and outcomes of 62 left sided EO-CRCs (EOLS-CRCs) and compared them to a group of late onset (?65) LS-CRCs (LOLS-CRCs).
MATERIALS AND METHODS:
Samples were evaluated for pathological features and microsatellite instability (MSI). Overall survival (OS), disease free survival (DFS) and disease specific survival were evaluated in both groups.
RESULTS:

We have read with great interest the editorial “Mesh in a mess?” by Wexner and
White . We agree with the authors when they say that the potential
complications associated with mesh should not forestall the use of prosthetic
materials when benefits attributable to mesh are demonstrated, as occurs in the
prevention of parastomal hernia. This also applies to groin hernia surgery.