The Influence of Catechol-O-Methyltransferase (COMT) Val158Met Gene Polymorphism, Persistence, and Attentional Characteristics on Novelty Seeking
Over the last five decades, a number of biological oriented personality theories have been proposed
to explain how anatomical and functional differences in the human brain are responsible for
individual differences in personality. Catechol-O-methyltransferase (COMT) gene for the Val158Met
single nucleotide polymorphism (rs4680) is known to influence the activity of the enzyme responsible
for dopamine metabolism and has been linked with various aspect of personality dimensions and