corticostriatal synaptic plasticity

Microscopio Neurolucida

Italiano

Microscopio Neurolucida (analisi morfologiche): permette analisi neuronali di tipo morfologico molto accurate. In particolare, nel campo della psicobiologia, tali analisi permettono lo studio della neuroplastità in termini di rimodellamento dendritico.

Intermittent theta-burst stimulation rescues dopamine-dependent corticostriatal synaptic plasticity and motor behavior in experimental parkinsonism. Possible role of glial activity.

Background: Recent studies support the therapeutic utility of repetitive transcranial magnetic stimulation in Parkinson's disease (PD), whose progression is correlated with loss of corticostriatal long-term potentiation and long-term depression. Glial cell activation is also a feature of PD that is gaining increasing attention in the field because astrocytes play a role in chronic neuroinflammatory responses but are also able to manage dopamine (DA) levels.

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