Putative receptors for gravity sensing in mammalian cells: The effects of microgravity
Gravity is a constitutive force that influences life on Earth. It is sensed and translated into biochemical stimuli through the so called "mechanosensors", proteins able to change their molecular conformation in order to amplify external cues causing several intracellular responses. Mechanosensors are widely represented in the human body with important structures such as otholiths in hair cells of vestibular system and statoliths in plants.